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Projects on Purna AI: a cleaner way to organize research work
Platform Updates
· 6 min read

Projects on Purna AI: a cleaner way to organize research work

Projects now keep chats, files, jobs, and outputs organized in one workspace on Purna AI's Molecular Intelligence Platform.

This Week on Purna AI Molecular Intelligence Platform
Platform Updates
· 6 min read

This Week on Purna AI Molecular Intelligence Platform

New on MIP this week: publication-quality scientific figures on demand, and protein embeddings and mutation likelihoods with ESM-2 and AbLang-2.

De Novo Enzyme Design with Diffusion Models: A Practical Guide
Drug Discovery
· 14 min read

De Novo Enzyme Design with Diffusion Models: A Practical Guide

How diffusion models like DISCO are changing de novo enzyme design, and how to move from a SMILES string to a testable candidate enzyme.

From Sequence to Structure to Function: How AI Connects the Dots in Biology
AI Research
· 20 min read

From Sequence to Structure to Function: How AI Connects the Dots in Biology

AI connects sequence analysis, structure prediction, and functional assessment into one continuous pipeline instead of fragmented tools.

Computational Drug Target Discovery: A Guide for Research Teams
Drug Discovery
· 19 min read

Computational Drug Target Discovery: A Guide for Research Teams

How computational approaches identify and validate drug targets using multi-omics data, genetic evidence, structural druggability, and AI prioritization.

AI in Proteomics: From Mass Spectrometry to Protein Function Prediction
AI Research
· 18 min read

AI in Proteomics: From Mass Spectrometry to Protein Function Prediction

How AI is transforming proteomics workflows, from peptide identification and quantification to PTM prediction, function annotation, and multi-omics integration.

AI for Rare Disease Diagnosis: Current Progress and What Comes Next
AI Research
· 17 min read

AI for Rare Disease Diagnosis: Current Progress and What Comes Next

AI rare disease diagnosis is advancing fast. We cover DeepRare, GeneDx, real accuracy numbers, and what still requires human expertise.

Open-Source vs Commercial Bioinformatics Platforms: Which Is Right for Your Lab?
Engineering
· 16 min read

Open-Source vs Commercial Bioinformatics Platforms: Which Is Right for Your Lab?

Honest comparison of open-source and commercial bioinformatics platforms covering TCO, compliance, scalability, and a decision framework for lab leads.

How to Read a Genomic Report: A Guide for Clinicians
Molecular Intelligence
· 16 min read

How to Read a Genomic Report: A Guide for Clinicians

Learn how to read a genomic report step by step. Covers variant classifications, ACMG criteria, when to act, and common mistakes.

Protein-Ligand Docking in the Age of AI: Classical vs Deep Learning Approaches
Drug Discovery
· 14 min read

Protein-Ligand Docking in the Age of AI: Classical vs Deep Learning Approaches

Compare classical protein-ligand docking tools like AutoDock Vina with AI approaches like DiffDock. Practical guide for drug discovery teams.

Best Bioinformatics Platforms in 2026: Galaxy, Terra, and Cloud Alternatives Compared
Engineering
· 19 min read

Best Bioinformatics Platforms in 2026: Galaxy, Terra, and Cloud Alternatives Compared

Comprehensive comparison of the best bioinformatics platforms in 2026 covering Galaxy, Terra, DNAnexus, LatchBio, and AI-native alternatives.

How AI Is Compressing Drug Discovery Timelines
Drug Discovery
· 15 min read

How AI Is Compressing Drug Discovery Timelines

Where AI is actually saving time in drug discovery, from target identification to lead optimization, with real examples and honest limits.

PyMOL vs ChimeraX vs Molstar: Protein Visualization Tools Compared
AI Research
· 19 min read

PyMOL vs ChimeraX vs Molstar: Protein Visualization Tools Compared

Practical comparison of PyMOL, ChimeraX, and Molstar covering rendering, scripting, file formats, and when to use each protein visualization tool.

How to Query Biological Databases Using Natural Language
Platform Updates
· 16 min read

How to Query Biological Databases Using Natural Language

Learn how natural language biological database queries replace multi-tool workflows. Query ClinVar, gnomAD, UniProt, OMIM, PDB, and PharmGKB in seconds.

What Is a Variant of Uncertain Significance (VUS) and How Do You Resolve One?
Molecular Intelligence
· 17 min read

What Is a Variant of Uncertain Significance (VUS) and How Do You Resolve One?

A variant of uncertain significance (VUS) lacks enough evidence for classification. Learn what causes VUS, how reclassification works, and how to resolve them.

AlphaFold 3 vs Boltz-2 vs ESMFold: Protein Structure Prediction Tools Compared
AI Research
· 18 min read

AlphaFold 3 vs Boltz-2 vs ESMFold: Protein Structure Prediction Tools Compared

Head-to-head comparison of AlphaFold 3, Boltz-2, and ESMFold covering accuracy, speed, licensing, and practical recommendations for each use case.

Bioinformatics Without Coding: How AI Is Making Computational Biology Accessible
Engineering
· 17 min read

Bioinformatics Without Coding: How AI Is Making Computational Biology Accessible

How natural language interfaces and AI-powered platforms are making bioinformatics without coding a reality for wet lab scientists and non-programmers.

Genomics vs Proteomics vs Transcriptomics: What Researchers Need to Know
AI Research
· 12 min read

Genomics vs Proteomics vs Transcriptomics: What Researchers Need to Know

A clear comparison of genomics, proteomics, and transcriptomics: what each measures, when to use which, and how multi-omics integration changes research.

How to Predict the Impact of Protein Mutations on Structure and Function
AI Research
· 12 min read

How to Predict the Impact of Protein Mutations on Structure and Function

A practical guide to predicting protein mutation effects using structure prediction, stability analysis, conservation scoring, and AI tools.

AI for Biology: What's Actually Working in 2026
AI Research
· 12 min read

AI for Biology: What's Actually Working in 2026

A practical look at where AI is making real progress in biology, from genomic interpretation and protein design to drug discovery and rare disease diagnosis.

What Is Molecular Intelligence? The Definitive Guide
Molecular Intelligence
· 15 min read

What Is Molecular Intelligence? The Definitive Guide

Molecular intelligence is domain-trained AI that reasons across biological data — genomics, proteomics, structure, and clinical databases — in one workspace.

$10,000 in Free Research Credits for the Molecular Intelligence Platform
Building & Startups
· 7 min read

$10,000 in Free Research Credits for the Molecular Intelligence Platform

Purna AI is offering up to $10,000 in free credits for researchers working on multi-omics datasets. Here's who qualifies and how to apply.

From Variant to Visit: How Genomics Actually Changes Management
Molecular Intelligence
· 7 min read

From Variant to Visit: How Genomics Actually Changes Management

Genomic testing changes care when it shifts us from treating the average to treating the individual — altering drugs, doses, and surveillance.

How Molecular Intelligence Is Reshaping Drug Discovery
Drug Discovery
· 3 min read

How Molecular Intelligence Is Reshaping Drug Discovery

An overview of how AI-powered molecular intelligence platforms are accelerating the drug discovery pipeline from target identification to lead optimization.

Protein Folding Meets Generative AI: What It Means for Therapeutics
AI Research
· 3 min read

Protein Folding Meets Generative AI: What It Means for Therapeutics

Exploring the convergence of protein structure prediction and generative models, and how this impacts the design of next-generation therapeutics.

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